Boost Research

Acetyl-L-Tyrosine (500 mg)

  1. “N-Acetyl-L-Tyrosine.” N-Acetyl-L-Tyrosine, Nootropedia, 1 July 2016, www.nootropedia.com/n-acetyl-l-tyrosine/.
  1. Louis E. Banderet, Harris R. Lieberman, “Treatment with Tyrosine, a neurotransmitter precursor, reduces environmental stress in humans”,

Brain Research Bulletin, Volume 22, Issue 4, 1989, Pages 759-762, ISSN 0361-9230,

https://doi.org/10.1016/0361-9230(89)90096-8

(http://www.sciencedirect.com/science/article/pii/0361923089900968)

  1. www.raysahelian.com/tyrosine.html

  1. https://examine.com/supplements/l-tyrosine/

  1. https://pubmed.ncbi.nlm.nih.gov/?term=N-Acetyl-Tyrosine



Evodiamine (25 mg)

  1. Ko, Yong-Hyun et al. “Evodiamine Reduces Caffeine-Induced Sleep Disturbances and Excitation in Mice.” Biomolecules & Therapeutics Vol. 26,5 (2018): 432-438. doi:10.4062/biomolther.2017.146

  1. Gavaraskar K, Dhulap S, Hirwani RR. “Therapeutic and cosmetic applications of Evodiamine and its derivatives--A patent review” Fitoterapia. 2015;106:22–35. doi: 10.1016/j.fitote.2015.07.019

  1. Kobayashi Y. “The nociceptive and anti-nociceptive effects of evodiamine from fruits of Evodia rutaecarpa in mice.” Planta Med. 2003;69(5):425–428. doi:10.1055/s-2003-39701

  1. Wu P, Chen Y. “Evodiamine ameliorates paclitaxel-induced neuropathic pain by inhibiting inflammation and maintaining mitochondrial antioxidant functions.” Human Cell. 2019;32(3):251–259. doi:10.1007/s13577-019-00238-4

  1. Wang D, Wang C, Liu L, Li S. “Protective effects of Evodiamine in the experimental paradigm of Alzheimer's disease.” Cognitive Neurodynamics. 2018;12(3):303–313. doi:10.1007/s11571-017-9471-z





L-Theanine (200mg) 

  1. Gomez-Ramirez M, et al (2007). “The deployment of intersensory selective attention: a high-density electrical mapping study of the effects of theanine.” Clinical Neuropharmacology, 30(1):25-38. doi: 10.1097/01.WNF.0000240940.13876.17

  1. Rao TP1, et al (2015). “In Search of a Safe Natural Sleep Aid.” Journal of American College Nutrition, 34(5):436-47. doi: 10.1080/07315724.2014.926153

  1. Yokogoshi H, et al (1998). “Effect of theanine, r-glutamylethylamide, on brain monoamines and striatal dopamine release in conscious rats.” Neurochemical Research, 23(5):667-73. doi: 10.1023/A:1022490806093

  1. Sumathi T, et al (2016). “L-Theanine alleviates the neuropathological changes induced by PCB (Aroclor 1254) via inhibiting upregulation of inflammatory cytokines and oxidative stress in rat brain.” Environmental Toxicology and Pharmacology, 42:99-117. doi: 10.1016/j.etap.2016.01.008

  1. Takeda A, et al (2011). “Facilitated neurogenesis in the developing hippocampus after intake of theanine, an amino acid in tea leaves, and object recognition memory.” Cellular, Molecular Neurobiolgy, 31(7):1079-88. doi: 10.1007/s10571-011-9707-0



Green Tea Extract (50% EGCG) (300 mg)

  1. https://www.webmd.com/food-recipes/features/health-benefits-of-green-tea#1

  1. Forouzanfar, Ali et al. “The potential role of tea in periodontal therapy: An updated review.” Current Drug Discovery Technologies, 10.2174/1389200221666200127114119. 26 Jan. 2020, doi:10.2174/1389200221666200127114119

  1. Chacko, Sabu M et al. “Beneficial effects of green tea: a literature review.” Chinese Medicine Vol. 5 13. 6 Apr. 2010, doi:10.1186/1749-8546-5-13

  1. Ide, Kazuki et al. “Effects of Tea Catechins on Alzheimer's Disease: Recent Updates and Perspectives.” Molecules (Basel, Switzerland) vol. 23,9 2357. 14 Sep. 2018, doi:10.3390/molecules23092357

  1. Khan, Naghma, and Hasan Mukhtar. “Tea and health: studies in humans.” Current Pharmaceutical Design Vol. 19,34 (2013): 6141-7. doi:10.2174/1381612811319340008



Guarana Seed Extract (50% Caffeine) (300 mg)

  1. Patrick, Madison et al. “Safety of Guarana Seed as a Dietary Ingredient: A Review.” Journal of Agricultural and Food Chemistry Vol. 67,41 (2019): 11281-11287. doi:10.1021/acs.jafc.9b03781

  1. Moustakas, Dimitrios et al. “Guarana provides additional stimulation over caffeine alone in the planarian model.” PloS one vol. 10,4 e0123310. 16 Apr. 2015, doi:10.1371/journal.pone.0123310

  1. Bortolin, Rafael Calixto et al. “Guarana supplementation attenuated obesity, insulin resistance, and adipokines dysregulation induced by a standardized human Western diet via brown adipose tissue activation.” Phytotherapy Research : PTR Vol. 33,5 (2019): 1394-1403. doi:10.1002/ptr.6330

  1. Schimpl, Flávia Camila et al. “Guarana: revisiting a highly caffeinated plant from the Amazon.” Journal of Ethnopharmacology Vol. 150,1 (2013): 14-31. doi:10.1016/j.jep.2013.08.023

  1. Angelo, Paula C S et al. “Guarana (Paullinia cupana var. sorbilis), an anciently consumed stimulant from the Amazon Rainforest: the seeded-fruit transcriptome.” Plant Cell Reports Vol. 27,1 (2008): 117-24. doi:10.1007/s00299-007-0456-y






Phosphatidylserine (200 mg)

  1. Kingsley, M. Effects of Phosphatidylserine Supplementation on Exercising Humans. Sports Medicine 36, 657–669 (2006). https://doi.org/10.2165/00007256-200636080-00003

  1. J. Baumeister, T. Barthel, K.R. Geiss & M. Weiss (2008) Influence of phosphatidylserine on cognitive performance and cortical activity after induced stress, Nutritional Neuroscience, 11:3, 103-110, DOI: 10.1179/147683008X301478

  1. Kingsley, Michael I., et al. "Effects of phosphatidylserine on exercise capacity during cycling in active males." Medicine & Science in Sports & Exercise 38.1 (2006): 64-71.

  1. Hellhammer, Juliane, et al. "Omega-3 fatty acids administered in phosphatidylserine improved certain aspects of high chronic stress in men." Nutrition Research 32.4 (2012): 241-250.

  1. Wells, Adam J., et al. "Phosphatidylserine and caffeine attenuate postexercise mood disturbance and perception of fatigue in humans." Nutrition Research 33.6 (2013): 464-472.