Shield Research

Vitamin C (Ascorbic Acid): 500mg (NO REFERENCES FOR VITAMINS)

Elderberry: 200mg

  1. Nowak, Dariusz et al. “Multidimensional comparative analysis of phenolic compounds in organic juices with high antioxidant capacity.” Journal of the science of food and agriculture vol. 97,8 (2017): 2657-2663. doi:10.1002/jsfa.8089

  1. Viapiana, Agnieszka, and Marek Wesolowski. “The Phenolic Contents and Antioxidant Activities of Infusions of Sambucus nigra L.” Plant foods for human nutrition (Dordrecht, Netherlands) vol. 72,1 (2017): 82-87. doi:10.1007/s11130-016-0594-x

  1. Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6.

  1. Roschek B, Fink RC, McMichael MD, et al. Elderberry flavonoids bind to and prevent H1N1 infection in vitro. Phytochemistry 2009;70:1255-61. 

  1. Tiralongo E, Wee SS, Lea RA. Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial. Nutrients. 2016 Mar 24;8(4). pii: E182. 

Echinacea: 200mg

  1. Hu, C. and Kitts, D. D. Studies on the antioxidant activity of Echinacea root extract. J Agric Food Chem 2000;48(5):1466-1472. View abstract.

  1. Steinmuller, C., Roesler, J., Grottrup, E., Franke, G., Wagner, H., and Lohmann-Matthes, M. L. Polysaccharides isolated from plant cell cultures of Echinacea purpurea enhance the resistance of immunosuppressed mice against systemic infections with Candida albicans and Listeria monocytogenes. Int.J Immunopharmacol. 1993;15(5):605-614. View abstract.

  1. Woelkart, K., Koidl, C., Grisold, A., Gangemi, J. D., Turner, R. B., Marth, E., and Bauer, R. Bioavailability and pharmacokinetics of alkamides from the roots of Echinacea angustifolia in humans. J Clin Pharmacol 2005;45(6):683-689. View abstract.

  1. Barrett B, Brown R, Rakel D. et al. Echinacea for treating the common cold: a randomized trial. Ann Intern Med 2010;153:769-77. 

  1. Barrett B, Vohmann M, Calabrese C. Echinacea for upper respiratory infection. J Fam Pract 1999;48:628-35. 
  2. Barrett B. Medicinal properties of Echinacea: a critical review. Phytomedicine 2003;10:66-86. 

Licorice Extract (Root 16% Glycyrrhizic Acids): 150mg

  1. Davis EA, Morris DJ. Medicinal uses of licorice through the millennia: the good and plenty of it. Mol Cell Endocrinol. 1991;78(1-2):1-6. View abstract.

  1. Fuhrman, B., Volkova, N., Kaplan, M., Presser, D., Attias, J., Hayek, T., and Aviram, M. Antiatherosclerotic effects of licorice extract supplementation on hypercholesterolemic patients: increased resistance of LDL to atherogenic modifications, reduced plasma lipid levels, and decreased systolic blood pressure. Nutrition 2002;18(3):268-273. View abstract.

  1. Ruetzler K, Fleck M, Nabecker S, Pinter K, Landskron G, Lassnigg A, You J, Sessler DI. A randomized, double-blind comparison of licorice versus sugar-water gargle for prevention of postoperative sore throat and postextubation coughing. Anesth Analg. 2013 Sep;117(3):614-21. View abstract.

  1. Mattarello MJ, Karbowiak I, Ermolao A, and et al. Licorice reduces body fat mass in obese men and women. 83rd Annual Meeting of the Endocrine Society, June 20-23 2001;abstract P1-573.

  1. Agarwal, A., Gupta, D., Yadav, G., Goyal, P., Singh, P. K., and Singh, U. An evaluation of the efficacy of licorice gargle for attenuating postoperative sore throat: a prospective, randomized, single-blind study. Anesth Analg 2009;109(1):77-81. View abstract.

Organic Astragalus Extract: 100mg

  1. Shahzad, Muhammad et al. “The Antioxidant Effects of Radix Astragali (Astragalus membranaceus and Related Species) in Protecting Tissues from Injury and Disease.” Current drug targets vol. 17,12 (2016): 1331-40. doi:10.2174/1389450116666150907104742

  1. Block, Keith I, and Mark N Mead. “Immune system effects of echinacea, ginseng, and astragalus: a review.” Integrative cancer therapies vol. 2,3 (2003): 247-67. doi:10.1177/1534735403256419

  1. Auyeung, Kathy K et al. “Astragalus membranaceus: A Review of its Protection Against Inflammation and Gastrointestinal Cancers.” The American journal of Chinese medicine vol. 44,1 (2016): 1-22. doi:10.1142/S0192415X16500014

  1. Butkutė, Bronislava et al. “Mineral and Phytochemical Profiles and Antioxidant Activity of Herbal Material from Two Temperate Astragalus Species.” BioMed research international vol. 2018 6318630. 21 Jan. 2018, doi:10.1155/2018/6318630

  1. Liu, Ping et al. “Anti-Aging Implications of Astragalus Membranaceus (Huangqi): A Well-Known Chinese Tonic.” Aging and disease vol. 8,6 868-886. 1 Dec. 2017, doi:10.14336/AD.2017.0816

Maitake: 100mg

  1. Mayell, M. “Maitake extracts and their therapeutic potential.” Alternative medicine review : a journal of clinical therapeutic vol. 6,1 (2001): 48-60.

  1. He, Xirui et al. “Polysaccharides in Grifola frondosa mushroom and their health promoting properties: A review.” International journal of biological macromolecules vol. 101 (2017): 910-921. doi:10.1016/j.ijbiomac.2017.03.177

  1. He, Yanli et al. “Grifola frondosa polysaccharide: a review of antitumor and other biological activity studies in China.” Discovery medicine vol. 25,138 (2018): 159-176.

  1. Mallard, Brody et al. “Synergistic immuno-modulatory activity in human macrophages of a medicinal mushroom formulation consisting of Reishi, Shiitake and Maitake.” PloS one vol. 14,11 e0224740. 7 Nov. 2019, doi:10.1371/journal.pone.0224740

  1. Wesa, Kathleen M et al. “Maitake mushroom extract in myelodysplastic syndromes (MDS): a phase II study.” Cancer immunology, immunotherapy : CII vol. 64,2 (2015): 237-47. doi:10.1007/s00262-014-1628-6

Reishi: 75mg

  1. Rani, P et al. “Antioxidant Potential of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Higher Basidiomycetes) Cultivated on Artocarpus heterophyllus Sawdust Substrate in India.” International journal of medicinal mushrooms vol. 17,12 (2015): 1171-7. doi:10.1615/intjmedmushrooms.v17.i12.70
  2. Cilerdzic, Jasmina et al. “Genoprotective Capacity of Alternatively Cultivated Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Basidiocarps.” International journal of medicinal mushrooms vol. 18,12 (2016): 1061-1069. doi:10.1615/IntJMedMushrooms.v18.i12.10

  1. Mohsin, Mohammed et al. “Determination of the antioxidant activity and polyphenol contents of wild Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (W.Curt. Fr.) P. Karst. (higher Basidiomycetes) from central Himalayan hills of India.” International journal of medicinal mushrooms vol. 13,6 (2011): 535-44. doi:10.1615/intjmedmushr.v13.i6.50

  1. Sudheer, Surya et al. “Determination of the Biological Efficiency and Antioxidant Potential of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Cultivated Using Different Agro-Wastes in Malaysia.” International journal of medicinal mushrooms vol. 20,1 (2018): 89-100. doi:10.1615/IntJMedMushrooms.2017024588

  1. Cizmarikova, Martina. “The Efficacy and Toxicity of Using the Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), and Its Products in Chemotherapy (Review).” International journal of medicinal mushrooms vol. 19,10 (2017): 861-877. doi:10.1615/IntJMedMushrooms.2017024537

Propolis: 50mg

  1. Patel, Seema. “Emerging Adjuvant Therapy for Cancer: Propolis and its Constituents.” Journal of dietary supplements vol. 13,3 (2016): 245-68. doi:10.3109/19390211.2015.1008614

  1. Przybyłek, Izabela, and Tomasz M Karpiński. “Antibacterial Properties of Propolis.” Molecules (Basel, Switzerland) vol. 24,11 2047. 29 May. 2019, doi:10.3390/molecules24112047

  1. de Groot, Anton C. “Propolis: a review of properties, applications, chemical composition, contact allergy, and other adverse effects.” Dermatitis : contact, atopic, occupational, drug vol. 24,6 (2013): 263-82. doi:10.1097/DER.0000000000000011

  1. Oryan, Ahmad et al. “Potential role of propolis in wound healing: Biological properties and therapeutic activities.” Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol. 98 (2018): 469-483. doi:10.1016/j.biopha.2017.12.069

  1. Sforcin, José M. “Biological Properties and Therapeutic Applications of Propolis.” Phytotherapy research : PTR vol. 30,6 (2016): 894-905. doi:10.1002/ptr.5605

Chaga: 50mg

  1. Géry, Antoine et al. “Chaga ( Inonotus obliquus), a Future Potential Medicinal Fungus in Oncology? A Chemical Study and a Comparison of the Cytotoxicity Against Human Lung Adenocarcinoma Cells (A549) and Human Bronchial Epithelial Cells (BEAS-2B).” Integrative cancer therapies vol. 17,3 (2018): 832-843. doi:10.1177/1534735418757912

  1. Balandaykin, Mikhail E, and Ivan V Zmitrovich. “Review on Chaga Medicinal Mushroom, Inonotus obliquus (Higher Basidiomycetes): Realm of Medicinal Applications and Approaches on Estimating its Resource Potential.” International journal of medicinal mushrooms vol. 17,2 (2015): 95-104. doi:10.1615/intjmedmushrooms.v17.i2.10

  1. Nagajyothi, P C et al. “Mycosynthesis: antibacterial, antioxidant and antiproliferative activities of silver nanoparticles synthesized from Inonotus obliquus (Chaga mushroom) extract.” Journal of photochemistry and photobiology. B, Biology vol. 130 (2014): 299-304. doi:10.1016/j.jphotobiol.2013.11.022

  1. Park, Yoo Kyoung et al. “Chaga mushroom extract inhibits oxidative DNA damage in human lymphocytes as assessed by comet assay.” BioFactors (Oxford, England) vol. 21,1-4 (2004): 109-12. doi:10.1002/biof.552210120

  1. Ham SS, Kim SH, Moon SY, et al. Antimutagenic effects of subfractions of Chaga mushroom (Inonotus obliquus) extract. Mutat Res 2009;672(1):55-9. View abstract.

Zinc Citrate (32% Yielding 25mg): 80mg (NO REFERENCE)